TRIDENOSEN is a potent dilator of the small arteries of the muscles of the body and heart. Adenosine. Nicotinic acid and DADA all dilate blood vessels that supply muscles. The reduction in vascular resistance produced by these agents leads to an increase in ease of blood flow, oxygen supply, and muscle perfusion. This increased blood flow leads to increased CO2 and lactic acid removal, reducing fatigue and muscle damage during maximal work periods. Experimental studies show that the blood supply to heart muscle is increased by more that 100% by infusion with adenosine compounds, and to skeletal muscle by 92%.
Magnesium and potassium aspartates are used in the treatment of fatigue and exhaustion in humans, and of the sodium / potassium imbalance which accompanies these fatigue states. Selenium and potassium aspartates are potent anti-oxidants, and help to limit muscle damage or azoturia incurred as a indicating that less muscle cell damage has been incurred.
TRIDENOSEN should be used to prevent cramping and Tying up (Rhabdomyolysis or azoturia). It can be successfully used to counter fatigue states, and as an aid to recovery after hard work.
TRIDENOSEN is of value in cases of “heart strain” as evidenced by ECG “T” wave changes.
DOSAGE AND ADMINISTRATION
Horse: Adult 15 – 25mL once or twice weekly
Foal 5mL once or twice weekly
Administer TRIDENOSEN by intramuscular injection, or slow intravenous injection under the direction of a veterinary surgeon.
COMPOSITION
EACH ML CONTAINS;
Adenosine triphosphate (ATP) 2mg
Nicotinic acid 20mg
Magnesium aspartate 20mg
Potassium aspartate 20mg
Di-isopropylamine dichloroacetate 50mg
Sodium selenite 500ug
WARNINGS
Do not administer vasodilating agents to animals in shock. For horses destined for human consumption, do not administer within 28 days of slaughter.
STORAGE
Store below 25 celcius (air conditioning). Protect from light
PRESENTATION
100mL sterile multi-dose glass vial.
