Macrosyn

Macrosyn Injectable Solution is an antibiotic indicated for the treatment of bovine respiratory disease (BRD), infectious bovine keratoconjunctivitis (pinkeye), and foot rot in beef and non-lactating dairy cattle and for treatment and control of swine respiratory disease (SRD) in swine. Each ml contains 100 mg tulathromycin. The usual recommended dosage of Macrosyn is 1.1 ml per 100 lbs. body weight, given in the neck. Do not administer more than 10 ml SQ per injection site in cattle. One dose provides up to 7-14 days BRD treatment and control. Do not administer more than 5 ml IM per injection site in swine. Not for use in female dairy cattle 20 months of age or older, or in calves to be processed for veal. Tulathromycin.

BRD – Macrosyn Injectable Solution is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis; and for the control of respiratory disease in cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, Histophilus somni, and Mycoplasma bovis. IBK – Macrosyn Injectable Solution is indicated for the treatment of infectious bovine keratoconjunctivitis (pinkeye) associated with Moraxella bovis.

Foot Rot – Macrosyn Injectable Solution is indicated for the treatment of bovine foot rot (interdigital necrobacillosis) associated with Fusobacterium necrophorum and Porphyromonas levii.

SRD – Macrosyn Injectable Solution is indicated for the treatment of swine respiratory disease (SRD) associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, Bordetella bronchiseptica, Haemophilus parasuis, and Mycoplasma hyopneumoniae; and for the control of SRD associated with Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae in groups of pigs where SRD has been diagnosed.

 

Dosage & Administration

Cattle

• Subcutaneous use.
• A single subcutaneous injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to 1 ml/40 kg bodyweight).
• For treatment of cattle over 300 kg bodyweight, divide the dose so that no more than 7.5 ml are injected at one site.

Pigs

• Intramuscular use.
• A single intramuscular injection of 2.5 mg tulathromycin/kg bodyweight (equivalent to 1 ml/40 kg bodyweight) in the neck.
• For treatment of pigs over 80 kg bodyweight, divide the dose so that no more than 2 ml are injected at one site.
• For any respiratory disease, it is recommended to treat animals in the early stages of the disease and to evaluate the response to treatment within 48 hours after injection. If clinical signs of respiratory disease persist or increase, or if relapse occurs, treatment should be changed, using another antibiotic, and continued until clinical signs have resolved.

Sheep

• Intramuscular use.
• A single intramuscular injection of 2.5 mg tulathromycin/kg body weight (equivalent to 1 ml/40 kg body weight) in the neck.

To ensure correct dosage bodyweight should be determined as accurately as possible to avoid underdosing.

 

Withdrawals

Cattle –

• Milk:Not authorised for use in animals producing milk for human consumption
• Meat:22 days

Sheep

• Meat:16 days

Pig

• Meat:13 days

Do not use in pregnant animals, which are intended to produce milk for human consumption, within 2 months of expected parturition